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Desmosome

[dɛsmɔsɔm]
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Définitions de « desmosome »

Desmosome - Nom commun

  • (Histologie) Zone spécialisée assurant l'adhésion et la communication entre les membranes de deux cellules adjacentes.

    Les desmosomes sont fréquents dans la peau, où ils maintiennent l'intégrité de l'épithélium, constamment soumis à des frottements et des déformations.
    — Patricia C. Cross, K. Lynne Mercer

Étymologie de « desmosome »

Du grec ancien desmos (« lien ») et soma (« corps »).

Usage du mot « desmosome »

Évolution historique de l’usage du mot « desmosome » depuis 1800

Synonymes de « desmosome »

Citations contenant le mot « desmosome »

  • To tease out the function of desmosomes in cell signaling and migration, Dubash has concentrated on a few of the individual protein components. In a study published in 2018, Dubash and four of his undergraduate researchers showed that the protein Desmoplakin, a part of the desmosome that is inside the cell, helps coordinate cellular migration.
    News — Cells on the Move - News
  • For proteins detected in every sample, significantly decreased abundance (determined by TMT tag count at the spectral peak) of the desmosome proteins desmoglein-1 (DSG1) (Log2FC − 0.26, p = 0.02), desmocollin-1 (DSC1) (− 0.27, p = 0.02) and junctional plakoglobin (JUP) (− 0.23, p = 0.04), and increased abundance of KRT6A (0.68, p = 0.01) was observed when the BPD and No BPD groups were compared (Table 2). No significant differences were noted for DSG1, DSC1 and JUP between the No BPD and Term groups (Fig. 2).
    Nature — Modulation of pulmonary desmosomes by inhaler therapy in preterm-born children with bronchopulmonary dysplasia | Scientific Reports
  • Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2,000 to 5,000 people worldwide. Researchers from the group of Eva van ...
    From mutation to arrhythmia: Desmosomal protein breakdown as an underlying mechanism of cardiac disease
  • Researchers from Osaka University find that patient-derived cardiomyocytes carrying a mutation associated with arrhythmogenic cardiomyopathy exhibit the decreased contraction and impaired desmosome assembly seen in this disease
    EurekAlert! — My heart will go on: Patient-derived heart ce | EurekAlert!
  • The researchers discovered that iASPP had a previously unknown role in controlling desmosomes – one of the main structures that 'glue' individual heart muscle cells (cardiomyocytes) together. The genetic defect was shown to weaken desmosome function at the junctions of heart muscle cells: this affected the structural integrity of the heart, making mice lacking iASPP prone to ARVC.
    Protein clue to sudden cardiac death | University of Oxford

Traductions du mot « desmosome »

Langue Traduction
Anglais desmosome
Espagnol desmosome
Italien desmosome
Allemand desmosom
Chinois 桥粒
Arabe ديسموسوم
Portugais desmotivado
Russe десмосома
Japonais デスモソーム
Basque desmosome
Corse desmosome
Source : Google Translate API


Sources et ressources complémentaires

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Source : Google Books Ngram Viewer, application linguistique permettant d’observer l’évolution au fil du temps du nombre d'occurrences d’un ou de plusieurs mots dans les textes publiés.